In this interesting research study using new and novel techniques Professor Anthony J Sargeant was able to show how during rehabilitation of young Military personnel work was shared unequally between a previously injured compared with an uninjured leg. In the bipedal cycling task the contribution of work from the previously injured leg was 40% of that of the uninjured leg. The difference in forces generated and work performed was similar to the massive loss of muscle fibre cross-sectional area reported in another study published in the same year (Clinical Science and Molecular Medicine. 1977 Apr;52(4):337-342). Clearly asymmetry of this magnitude may well explain why, many years after injury, a difference in muscle size and function often persists despite intensive rehabilitation (but rehabilitation which often involves bipedal exercise).
Clinical Science and Molecular Medicine
Clin Sci Mol Med. 1977 Aug;53(2):183-8